The work was commissioned by the rich merchant Matthäus Landauer of Nuremberg for a chapel dedicated to the Holy Trinity and All the Saints in the Zwölfbrüderhaus ("House of Twelve Brothers"), which he had founded with Erasmus Schiltkrot in 1501.
His manuscript illumination The Holy Trinity particularly demonstrates the influence of Albrecht Dürer's Adoration of the Trinity, also known as the Landauer Altarpiece, painted in 1511.
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