Barren County is served by Interstate 65, which goes through the northwest part of the county, and the Louie B. Nunn Cumberland Parkway, a former toll road that is designated to be part of the future Interstate 66 corridor.
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Glasgow, the county seat, has numerous manufacturing facilities, and is also a medical and retail hub for the area.
Viewers living in Warren, Butler, Hart, Edmonson, Barren, and Metcalfe Counties in South Central Kentucky are eligible to switch to Bowling Green local stations.
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In 1950, Horse Cave, located in Hart County; Cave City, in Barren County; and the Kentucky Board of Education held a meeting that approved the union of the two districts because of the low student numbers in both school systems.