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The Biqa Valley is watered by two rivers that rise in the watershed near Baalbek: the Orontes flowing north (in Arabic it is called Nahr al Asi, "the Rebel River", because this direction is unusual), and the Litani flowing south into the hill region of the southern Biqa Valley, where it makes an abrupt turn to the west in southern Lebanon and is thereafter called the Al Qasmiyah River.
In 1623, Mustafa Pasha, the new governor of Damascus, engaged him in battle, and was decisively defeated at Anjar in the Biqa Valley.