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In the 1945 film Caesar and Cleopatra, based on the play by George Bernard Shaw, he is played by Stewart Granger, and is depicted as being somewhat in love with Cleopatra.
Later literary accounts often attributed Pompey's murder solely to Septimius, as in the poem Pharsalia by the Roman poet Lucan, or in modern fictionalizations such as the George Bernard Shaw play Caesar and Cleopatra, and the HBO television series Rome (depicted in the episodes "Pharsalus" and "Caesarion").
In 1951, Brook was asked by Laurence Olivier to join his company at the St James’s Theatre in Shakespeare’s Anthony and Cleopatra and George Bernard Shaw’s Caesar and Cleopatra.
He created the role of Orsini-Rosenberg in the original New York production of Amadeus and appeared with Sir Rex Harrison in the 1979 revival of Shaw's Caesar and Cleopatra in the role of Pothinus.
Fellow Nobel Laureate (1925) Bernard Shaw cited Mommsen's interpretation of the last First Consul of the Republic, Julius Caesar, as one of the inspirations for his 1898 (1905 on Broadway) play, Caesar and Cleopatra.
She also appeared in All the Way Home, Oh! What a Lovely War, Caesar and Cleopatra, Tartuffe, The Balcony and The Boor (all at the Goodman Theatre, Chicago); and Curse of the Starving Class at the Tiffany Theatre (in Los Angeles).