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Louis de Lorraine known as the Cardinal de Guise (22 January 1575 – 21 June 1621, Saintes) was the third son of Henry I, Duke of Guise and Catherine of Cleves.
She was the daughter of Arnold, Duke of Guelders, and Catherine of Cleves, a great-aunt of Anne of Cleves.
Louise Marguerite of Lorraine (1588-1631) daughter of Henri, Duke of Guise and Catherine of Cleves, wife of François, Prince of Conti.