He planned its eastern and western terminals at deep-water ports, Fernandina (Port of Fernandina) on Amelia Island on the Atlantic side, and Cedar Key on the Gulf of Mexico, to provide for connection to ocean-going shipping.
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The farmland included cattle and orange groves; and Jackson piloted passenger and mail ships from Cedar Key to New Orleans and from Tampa to Cuba.
It was found in 28 of 72 rice rats at Cedar Key, Florida, with the number of flukes per infected rat ranging from one to 150 (average 17), and in five of six rice rats from Sapelo Island, Georgia, with two to 51 flukes per rat (average 18), but did not occur in more than 100 rice rats from freshwater marshes in Florida.
The naturalist John Muir visited Cedar Key in 1867 on his historic walk from Kentucky to Florida.