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In The New 52 (a reboot of the DC Comics universe) as part of the Forever Evil storyline, Cluemaster is among the villains that the Crime Syndicate of America recruited to join the Secret Society of Super Villains.
During the Forever Evil storyline, the Court of Owls see the news from the Crime Syndicate that the Justice League is "dead" and claims that the Court of Owls will prosper.
During the "Forever Evil" storyline, Doctor Destiny is among the villains recruited by the Crime Syndicate of America to join the Secret Society of Super Villains.
In The New 52 (a reboot of the DC Comics universe) as part of the Forever Evil storyline, Doctor Phosphorus is among the villains that the Crime Syndicate of America recruited to join the Secret Society of Super Villains.
In Forever Evil #1, the Crime Syndicate of America meet in Happy Harbor with an army of supervillains and declare that the Justice League is dead and that the world now belongs to the Crime Syndicate and the Secret Society of Super-Villains.
In the 2010 animated film Justice League: Crisis on Two Earths, Wonder Woman commandeers an attack plane from Owlman (an evil version of Batman) while the Justice League is on a parallel Earth dominated by their villainous counterparts, the Crime Syndicate.
In The New 52 (a reboot of the DC Comics universe), Johnny Quick is one of the members of the Crime Syndicate to arrive from Earth-3 at the conclusion of the "Trinity War" event.
During the Forever Evil storyline, Lion-Mane is among the villains recruited by the Crime Syndicate of America to join their Secret Society of Super Villains.
In The New 52 (a reboot of the DC Comics universe) as part of the Forever Evil storyline, Nocturna is among the villains recruited by the Crime Syndicate of America to join the Secret Society of Super Villains.
During the Forever Evil storyline, Dr. Thomas Morrow was seen at S.T.A.R. Labs' Detroit branch following the Crime Syndicate's invasion.