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In February 2006, Parker attended a benefit with former Pretender co-stars Michael T. Weiss and James Denton for Cure Autism Now.
With his wife Jo, Bill is a past Co-President of the Cure Autism Now Northwest chapter, now merged with Autism Speaks.
He provides unique insights into the nature of his autism, and perhaps autism in general, according to Autism Speaks, the former Cure Autism Now, scientists who studied his case, such as distinguished neuroscientist Dr. Michael Merzenich, and doctors, journalists, and authors at many major media companies such as ABC, CBS, National Geographic, New York Times, Scientific American, PBS, and CNN.