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Jessup Mill is an 102-year-old grist mill, standing on the banks of the Dan River, in the community of Collinstown in northwest Stokes County, North Carolina.
After a long, straight stretch, the route intersects US 311, NC 87 and NC 770 (Harrington Highway) just before it crosses the Dan River and enters Eden.
To the north of SR 41 are the watersheds of Little Falls Creek east of White Oak Mountain and the Bannister River west of the mountain; these streams empty into the Dan River at Danville and near South Boston, respectively.