In September 1993, he lost his first title shot to World Boxing Board Light Welterweight champion David Kamau.
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Danny Perez has fought many great fighters like Antonio Margarito (twice), Jose Luis Zertuche, Julio César García, Craig McEwan, Erislandy Lara, Jesse Brinkley, Grady Brewer, Julio César García, David Lopez, Sam Garr, and David Kamau.He lost a highly controversial majority decision to Golden Boy fighter Mcewan.