Matheson died on September 5, 1994 at Duke University Hospital from complications due to Hodgkin's disease.
Dr. Mario has served as a trustee of Duke University from 1989 to 2007, and chaired the Duke University Health System board of trustees from its inception until 2007.
On May 5, 2011, in a deal worth $25 million, MedCath sold most of its assets to a joint venture of LifePoint Hospitals and Duke University Health System.
During this period, he oversaw the development of the Duke University Health System, one of the most successful integrated academic health systems in the country and served as its first President and Chief Executive Officer.
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