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His one and only World Championship Grand Prix start came in 1975 when he replaced Arturo Merzario at Williams at short notice for the Swedish Grand Prix.
Following the agreement with Philip Morris that led to the creation of the Iso-Marlboro brand in Formula 1, Philip Morris commissioned Iso to construct 2 specially modified Leles for their Formula 1 Team Drivers Howden Ganley and Nanni Galli.
Brise made his Grand Prix debut on 27 April 1975 for Williams but after one race switched to Embassy Racing With Graham Hill run by former world champion driver Graham Hill, where he showed great potential.