The locations of the interchanges are: U.S. Route 52 between New Boston and Wheelersburg, State Route 140 near the Portsmouth city limit, Airport Road adjacent to the Greater Portsmouth Regional Airport / Access to Ohio State Route 335 just south of Minford, at Lucasville-Minford Road / County Route 28 near Rases Mountain Drive in Minford, and at U.S. 23 just north of Lucasville.
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