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This region roughly coincides with the Brazilian municipality of São Gabriel da Cachoeira and parts of Japurá, and shares international borders with the Venezuelan state of Amazonas (to the northeast), and the Colombian departments of Guainía (to north), Vaupés (to west) and Amazonas (to southwest).
Inírida, the capital city and a municipality of the Guainía Department in Colombia;
Inírida River, major tributary of the Guaviare River in the Guainía Department in Colombia;