He primarily painted portraits on commission for patrons such as the Duke of Buccleuch and Lord Bolingbroke.
The château was occupied during the last decades of his life by the exiled English politician Lord Bolingbroke (1678–1751), who wrote many of his works there.
It was frequented by 20 of the finest forerunners of the Age of Enlightenment, with regular attendees including Montesquieu, Helvétius, the marquis d'Argenson, Andrew Michael Ramsay, Horace Walpole and Viscount Bolingbroke.
The study of Shaftesbury and Bolingbroke wakened his interest in theology, and, breaking off his studies, he set out for Paris.
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He translated into French several works by Alexander Pope, Henry Bolingbroke, William Warburton's The Alliance between Church and State, (1736) as Dissertations sur l'Union de la Religion, de la Morale, et de la Politique (1742) and Baltasar Gracián's El político.
In a joint letter from Alexander Pope and Bolingbroke to Swift, dated December 1725, the ‘late ordinary’ is described ironically as the ‘great historiographer.’ The penitence of his clients is always described as so heartfelt that the latter are playfully called by Richard Steele ‘Lorrain's Saints’.