X-Nico

10 unusual facts about Human Leukocyte Antigen


HLA-DR1

HLA-DR1 (DR1) is a HLA-DR serotype that recognizes the DRB1*01 gene products.

HLA-DR10

HLA-DR10 (DR10) is a HLA-DR serotype that recognizes the DRB1*1001 gene product.

HLA-DR13

HLA-DR13(DR13) is a HLA-DR serotype that recognizes the DRB1*1301 to *13082, *1310 and some other *13 gene products.

HLA-DR16

HLA-DR16(DR16) is a HLA-DR serotype that recognizes the DRB1*1601, *1602 and *1604 gene products.

HLA-DR17

HLA-DR17 (DR17) is an HLA-DR serotype that recognizes the DRB1*0301 and *0304 gene products.

HLA-DR18

HLA-DR18 (DR18) is a HLA-DR serotype that recognizes the DRB1*0302 and *0303 gene products.

HLA-DR2

HLA-DR2 (DR2) of the HLA-DR serotype system, is a broad antigen serotype that is now preferentially covered by HLA-DR15 and HLA-DR16 serotype group.

HLA-DR8

HLA-DR8 (DR8) is a HLA-DR serotype that recognizes the DRB1*0801 to *0807, and *0810 to *0812 gene products.

HLA-DR9

HLA-DR09 (DR9) is a HLA-DR serotype that recognizes the DRB1*1001 gene product.

Manchester High School for Girls

Julia Bodmer, nee Pilkington, Manchester High School pupil: 1945 - 1953, discovered the details of the Human leukocyte antigen (HLA) with genetic differences causing transplant rejection, and was married to Sir Walter Bodmer, who was the first Professor of Genetics at the University of Oxford, Chancellor of the University of Salford from 1995 to 2005 and Principal from 1996 to 2005 of Hertford College, Oxford


HLA-DP

DPα and DPβ are encoded by two loci, HLA-DPA1 and HLA-DPB1, that are found in the MHC Class II (or HLA-D) region in the Human Leukocyte Antigen complex on human chromosome 6 (see protein boxes on right for links).

Persistent polyclonal B-cell lymphocytosis

Among them, it is associated with a particular genetic variant of the human leukocyte antigen called HLA-DR7.