Intrinsic factor, a glycoprotein produced by the parietal cells of the stomach, which is necessary for the absorption of vitamin B12
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Dr. William B. Castle, discoverer of intrinsic factor, introduced him to Dr. Sidney H. Ingbar with whom Tishler began work on the metabolic actions of thyroid hormone.
Intrinsic factor is essential for the uptake of 12vitamin B12 deficiency.