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In 1966, Riegle, then 28 years old and a moderate Republican, defeated incumbent Democratic U.S. Representative John C. Mackie to be elected from Michigan's 7th congressional district to the 90th Congress.
He was Genesee County surveyor, 1952–1956 and was elected State Highway Commissioner of Michigan, 1957 and reelected in 1961 to a new four-year term.
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Mackie's criticism's were rebuked by, George W. Romney, then the president of American Motors Corporation and leading proponent of compact cars in the United States.
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Mackie was elected as a Democrat from Michigan's 7th congressional district to the 89th United States Congress, serving from January 3, 1965 to January 3, 1967.
Defenders of some form of moral skepticism include David Hume, J. L. Mackie (1977), Max Stirner, Friedrich Nietzsche, Richard Joyce (2001), Michael Ruse, Joshua Greene, Richard Garner, Walter Sinnott-Armstrong (2006b), and the psychologist James Flynn.
Thomas T. Mackie, research/public health physician in the United States Army during World War II