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In 1877, pathologist Otto Bollinger described the presence of Actinomyces bovis in cattle, and shortly afterwards, James Israel discovered Actinomyces israelii in humans.
The agents of actinomycosis are now known to be endogenous organisms of the mucous membranes, in most cases Actinomyces israelii, a species named after surgeon James Israel, who first discovered its presence in humans in the late 1870s.
He was the son of James Israel Denneny who was a top lacrosse player in the late 19th century and was descended from the Dennenys of County Monaghan, Ireland.