After an investigation of a number of sites, the island of Culion was selected as a segregation colony in 1901.
St Mary's met these needs in a hospital attached to the main church building, and a separate leper house located at a "safe" distance from the town centre.
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$50,000 were given to the colony by the Second Philippine Commission on October 27, 1902 for the creation of the Culion Leper Colony under the Director of Health Victor G. Heiser.
Arning is known today for his medical studies done at the leper colony on Molokai.
The 1999 movie Molokai featuring Peter O'Toole and Kris Kristofferson focuses on the story of Father Damien and the leper colony.
Kapahei “Judge” Kauai Representative from Kauai-Contracted leprosy and was the leader of the leper colony during the Leper War.
“An Imbecile and an Idiot” (Byeongsin gwa mejeori, 1966) probes the spiritual malaise of the post-war Korean youth; This Paradise of Yours (Dangsindeurui cheonguk, 1976) explores the dialectics of charity and will to power, with the leper colony of Sorokdo Island as the backdrop; and The Fire Worshipers (Bihwa milgyo, 1985) meditates on the meaning of human rituals conducted in a Godless society when no ultimate guarantee of the absolute can be given.