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Along with his brother, he wrote the screenplay for Y tu mamá también (starring Gael García Bernal, Diego Luna and Maribel Verdú) and received the Silver Lion for best original screenplay in the 2001 edition of Venice International Film Festival.
Later that year he appeared on Antonio Banderas' second directorial effort Summer Rain (El Camino de los Ingleses), and in 2007 in the musical/comedy Scandalous (¿Por qué se frotan las patitas?) and Seven Billiard Tables (Siete mesas de billar francés), with Maribel Verdú.