Maryland | University of Maryland | Bethesda, Maryland | Annapolis, Maryland | Silver Spring, Maryland | Montgomery County, Maryland | U.S. Route 66 | U.S. Route 1 | Cumberland, Maryland | Governor of Maryland | Frederick, Maryland | Maryland House of Delegates | Hagerstown, Maryland | U.S. Route 6 | U.S. Route 101 | Route 66 | Emmitsburg, Maryland | Columbia, Maryland | Westminster, Maryland | U.S. Route 30 | New Jersey Route 4 | European route E65 | U.S. Route 40 | Laurel, Maryland | Howard County, Maryland | Havre de Grace, Maryland | California State Route 1 | University of Maryland, Baltimore | Bowie, Maryland | U.S. Route 1 in Maine |
Due to limitations in the highway in Port Deposit, including a steep hill and a low railroad bridge, the state highway has a truck bypass that uses MD 275, MD 276, and US 1 through Woodlawn and Rising Sun to connect Interstate 95 (I-95) with US 222 in Conowingo.