The Janissaries started accepting enrollment from outside the devshirmeh system first during the reign of Sultan Murad III (1546–1595) and completely stopped enrolling devshirmeh in 17th century.
Initially profiting from Ottoman support, Michael the Brave ascended to the throne in 1593, and attacked the troops of Murad III north and south of the Danube in an alliance with Transylvania's Sigismund Báthory and Moldavia's Aron Vodă (see Battle of Călugăreni).
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Moreover, it has been said that Nûr-Banû was related to Giorgio Baffo, as well as to Safiye Sultan, who was born Sofia Baffo, married to Nûr-Banû's son Murad III, and consequently became the next Valide Sultan of the Ottoman Empire when her son Mehmed III acceded to the throne.
Its founder, the Serbian Metropolitan of Herzegovina, later the Serbian Patriarch, Savatije Sokolović, was a kinsman of the Grand Vizier, Mehmed Pasha Sokolović (also known as Sokollu Mehmed Pasha), who was kidnapped from his Serbian home as a boy and rose to become one of the most renowned statesmen to three sultans -- Suleiman the Magnificent, Selim I and Murad III.