Francesco Anile has worked with some of the more notable international conductors, such as Nello Santi, Massimo Pradella, Niksa Bareza, Evelino Pidò, Maurizio Arena, Loris Voltolini, Stefano Ranzani, Maurizio Benini, Peter Mianiti, Antonio Pirolli, Gianpaolo Bisanti and Patrick Fourniller.
Past general music directors (GMD) of the company have included Niksa Bareza (1981-1990), Philippe Jordan (2001-2004), and Johannes Fritzsch (2006-2013).