Her children were raised in the Portuguese court, where they were known by their appellation Noronha (Portuguese translation of Noreña).
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After the death of Alfonso of Gijón y Noreña in 1398, Isabel fled to the court of her uncle, King John I of Portugal.
Once Alfonso was Count of Noreña, an Asturian village he had received from his father, Isabel's children used the Portuguese spelling Noronha as their family name.