Unlike similar schools such as the Illinois Mathematics and Science Academy and the North Carolina School of Science and Mathematics, CAMS is non-residential, drawing its students solely from most of Long Beach, portions of Los Angeles, and some cities of the South Bay region.
The creek flows through many of Durham's most historic and culturally significant areas, including Ninth Street, Downtown Durham, beneath Durham Athletic Park, The North Carolina School of Science and Mathematics, the Museum of Life and Science, the old Durham Landfill, Duke University East Campus, Northgate Mall, and towards the end crosses Fishdam Road.
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