CADASIL ("Cerebral Autosomal-Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy") is the most common form of hereditary stroke disorder, and is thought to be caused by mutations of the Notch 3 gene on chromosome 19.
There is evidence that activated Notch 1 and Notch 3 promote differentiation of progenitor cells into astroglia.
CADASIL syndrome (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy syndrome) is a hereditary stroke condition due to a Notch 3 gene mutation on Chromosome 19.
Notch | Notch-1 | Dixville Notch, New Hampshire | Notch 3 | Plymouth Notch, Vermont | Suprascapular notch | Stony Clove Notch | Notch-2 | Markus "Notch" Persson | Franconia Notch | Dixville Notch | Crawford Notch |