A street sign reading "Satartia - 7 miles" is featured in the 2000 movie O Brother, Where Art Thou.
In addition to rejuvenating Parton's then-lagging career, the album, along with the O Brother, Where Art Thou soundtrack and the work of Alison Krauss, is credited with making bluegrass a hugely popular musical genre during the early 2000s.
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Her soundtrack performances have led to further popularity, including the O Brother, Where Art Thou? soundtrack, which won the Grammy Award for Album of the Year in 2002 and is also credited with raising American interest in bluegrass, and the Cold Mountain soundtrack, which led to her performance at the 2004 Academy Awards.
His most famous compositions include "White Dove" and "The Fields Have Turned Brown." His arrangement of "Man of Constant Sorrow" was popularized in the 2000 film O Brother, Where Art Thou?
The first Hollywood film to utilize a digital intermediate process from beginning to end was O Brother, Where Art Thou? in 2000 and in Europe it was Chicken Run released that same year.
Indiana University Press' The Journal of Folklore Research has asserted that a Lloyd Chandler song on the album, "A Conversation With Death" was an early form of "O Death"—a song which Ralph Stanley won a Grammy award for, featured on the O Brother, Where Art Thou soundtrack.
A Canadian blues musician, Linden had previously participated in Down from the Mountain, a live performance of music from the Coens' O Brother, Where Art Thou?, and he performs several songs in the film.
The album was nominated for the BAFTA Award for Best Film Music (lost to the score of Moulin Rouge!) and the Grammy Award for "Best Compilation Soundtrack Album for a Motion Picture, Television or Other Visual Media" (lost to the score of O Brother, Where Art Thou?).
The Cox Family can be heard on the O Brother, Where Art Thou? soundtrack, and their 1994 collaboration with Alison Krauss (I Know Who Holds Tomorrow) won the 1995 Grammy Award for Best Southern, Country or Bluegrass Gospel Album.
McBride chose to include Dan Tyminski as a backing vocalist after hearing him sing "I Am a Man of Constant Sorrow" in the movie O Brother, Where Art Thou? She also said that she enjoyed Leslie Satcher's lyrics in the song, and said that she was laughing the first time she heard Satcher's demo.
NuBlues were discovered by Grammy Award-winning artist Chris Thomas King, known to many for his performance in O’ Brother Where Art Thou, but well known also as a performer in his own right.