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The Corumbá flows south from its source near Corumbá de Goiás, where there are spectacular waterfalls, is crossed by a major ridge on the Brasília-Goiânia highway east of Alexânia, passing near Pires do Rio and Caldas Novas, south of which it enters the Itumbiara Reservoir, the lake damming up the Paranaíba River, one of the main tributaries of the Paraná.