From August to late November, he took part in the Duke of York's expedition in Holland.
On 6 October 1799, a Franco-Dutch army under Guillaume Brune defeated an Anglo-Russian army under Ralph Abercromby and the Duke of York in the Battle of Castricum.
He went to Newfoundland a second time in 1790, and in 1794 served under the Duke of York in the Flanders Campaign.
He was promoted for his services to the rank of deputy inspector-general of hospitals, and had part of the direction of the medical service in the Duke of York's expedition to Den Helder.
The expedition was under the command of Admiral Adam Duncan and the Duke of York.
Prince Edward had orders from his brother Prince Frederick, the Duke of York, to restore a sense of military discipline at the garrison.
By Hurd's influence he was appointed in 1776 preceptor to the Prince of Wales and the Duke of York, and was made canon of Windsor.
He reported the impeachment of Lord Melville in 1806, the proceedings against the Duke of York in 1809, the trials of Lord Cochrane in 1814 and of Arthur Thistlewood in 1820, and the proceedings against Queen Caroline.
He was educated at the Royal Military College, Marlow, and given a commission in the 1st Royal Dragoons by the Duke of York on 7 May 1812, serving with his regiment in the Spanish peninsula.
He served in Flanders under the Duke of York, and in 1795 was promoted major, and purchased the lieutenant-colonelcy of the 19th regiment.
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His patrons included Angelica Catalani (an opera singer), JP Kemble, Sir Francis Burdett, Thomas Hope, George IV, the duke of York and his mistress Mary Anne Clarke.
For example from 1779–1803 the Duke of Bridgwater held it and from an unknown date until 1827 the British Commander-in-Chief Prince Frederick, Duke of York and Albany, famed for the nursery rhyme, the Duke of York Column was tenant of the lands.
Laffan treated troops in the Peninsular War, he was the personal physician (Physician-in-Ordinary) to Queen Victoria's father the Duke of Kent and also the Duke of York (an elder son of King George III).
She was the daughter of cartoonist and writer George du Maurier and his wife Emma Wightwick, the elder sister to actor Gerald du Maurier, the aunt of novelists Angela and Daphne du Maurier and great-granddaughter of Royal mistress of Prince Frederick, Duke of York and Albany Mary Anne Clarke.