Along with Richard Lerner, he was one of the critical players in the development of phage-display libraries, and surface-library chips.
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The invention of antibody phage display by laboratories at the MRC Laboratory of Molecular Biology led by Greg Winter and John McCafferty, The Scripps Research Institute led by Richard Lerner and Carlos F. Barbas and the German Cancer Research Centre by Frank Breitling and Stefan Dübel revolutionised antibody drug discovery.