Sampson County is the birthplace of William R. King, a politician and diplomat who was elected both to the House of Representatives and the Senate.
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Passing through rural Sampson County on a road with the street name Harrells Highway, NC 411 passes the western terminus of North Carolina Highway 903 and enters the town of Garland.
Located along the west side of Sampson County along the banks of South River at the Cumberland County, North Carolina line, Autryville is governed by a mayor and a five-member town commission.
Autryville is home to Micajah Autry, a Sampson County resident and son of Theophilus and Elizabeth (Crumpler) Autry who fought in the Battle of the Alamo alongside Davy Crockett.