The area now composing Denmark Township was long inhabited by the Seneca Indian tribe.
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In 1687 the governor of New France, the Marquis de Denonville, launched an attack against Seneca villages in what is now western New York.
On July 31, Major Andrew Williamson captured two white loyalists, who led his 330 men into an ambush prepared by their fellow Tories and Seneca Indians on the Keowee River.
Active in the troupes de la marine from an early age, he served with his father during a 1687 French military operation against the Seneca tribes of present-day western New York led by Governor of New France Jacques-René de Brisay de Denonville, Marquis de Denonville.
With Spring, Seneca leaders Guyasuta and Big Tree met Wayne at Legion Ville in March 1793 to discuss peace terms.
The Six Nations of the Grand River First Nation are the Mohawk, Cayuga, Onondaga, Oneida, Seneca, and Tuscarora.
At the time, it was still a wooded frontier and home to Seneca and Mohawk Indians.