The EyeWire project harnesses human computation in a game to trace neurons through images of a volume of retina obtained using SBEM.
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Practical SBFSEM was been invented in 2004 by Winfried Denk at the Max-Planck-Institute in Heidelberg and is commercially available from Gatan Inc.
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These extremely thin cuts are important for use with transmission electron microscope (TEM) and Serial Block-Face Scanning Electron Microscopy (SBFSEM), and are sometimes also important for light-optical microscopy.