The 2004 HBO television movie Something the Lord Made, based on Washingtonian writer Katie McCabe's 1989 article of the same name, was made about his role in the historic Blue Baby surgery, as was the 2003 public television documentary Partners of the Heart.
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LeBouef appeared as Harold Thomas the brother of the main character, Vivien Thomas, in the 2004 HBO movie Something the Lord Made which starred Mos Def.