The novel Phobos, published in 2011 and written by Steve Alten as the third and final part of his Domain trilogy, shows a fictional story where strangelets are unintentionally created at the Large Hadron Collider and escape from it to destroy the Earth.
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Examples include works by Jules Verne (The Mysterious Island), Arthur Conan Doyle (The Lost World), and Edgar Rice Burroughs (The Land That Time Forgot), and recent fiction such as Michael Crichton (Jurassic Park) and Steve Alten (the Meg series and The Loch).
In Steve Alten's The Loch the Loch Ness Monster is originally thought to be a guivre which got into Loch Ness through Moray Firth.