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De Pierro grew up in the small town of Échandens in Suisse Romande and initially began his career with local club Forward Morges before a move to the academy of FC Lausanne-Sport.
Praised for his formidable technique and many varied colors (His technique has been compared by the 2007 Revue Musicale de Suisse Romande to that of the legendary pianist Vladimir Horowitz and called him " a sensual gourmand of sound ") he has received critical acclaim for his interpretations of Transcriptions (including some of his own), French, Spanish and Romantic music.
As a soloist of international repute she has performed in concert with, among others, the BBC Symphony Orchestra in London, the Gewandhaus in Leipzig Germany, the NHK Symphony Orchestra in Tokyo, the Hallé Orchestra Manchester, La Suisse Romande and Montreal.
He came to Europe in 1972 and held 1st Concertmaster positions in Munich, Stuttgart, the Lucerne Festival Orchestra, the Zurich Symphony Orchestra and the Orchestre de la Suisse Romande in Geneva.