The center housed the Office of the Advocate General of the Missions (which oversaw the order's numerous, lucrative Indian Reductions), as well as a pharmacy (the city's first) opened and operated by an English Jesuit, Father Thomas Falkner.
Discovered in 1748 by Jesuit missionaries José Cardiel and Thomas Falkner, they originally named the waterway San José; its eventual name originated from the Araucanian Kem Kem ("gully").
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