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Although the term “Unitarian” was already known in England from the Latin Library of the Polish Brethren called Unitarians published in Amsterdam (1665-1668), and had been used in print before by Henry Hedworth (1673), Nye's book gave the term wider currency in English among antitrinitarian believers, and set off the Unitarian controversy.
The Calvinist minister Jedidiah Morse published the chapter separately, as part of his campaign against New England's liberal ministers—contributing to "the Unitarian Controversy" (1815) that eventually produced permanent schism among New England's Congregationalist churches.
Another brother, Samuel (1770–1821), also a clergyman, was corresponding secretary of the American Board of Commissioners for Foreign Missions in 1810, and in 1815 engaged in the Unitarian controversy, his immediate opponent being William Ellery Channing.