In 1945, representatives from 50 countries met in San Francisco for the United Nations Conference on International Organization.
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Kirk became involved in the formation of the United Nations Security Council, attending the Dumbarton Oaks Conference and the United Nations Conference on International Organization where the United Nations Charter was signed.
A "Declaration on the Essential Rights of Man" had been proposed at the 1945 San Francisco Conference which led to the founding of the United Nations, and the Economic and Social Council was given the task of drafting it.
Following World War II Zanella demanded the restoration of the Free State as a sovereign entity, but failed to receive support for his idea at the United Nations Conference on International Organization in San Francisco.
He was also a member and vice-chairman to the United Nations Conference on International Organization in 1945 that chartered the United Nations.
He served as a military adviser to the Joint Chiefs of Staff at the June 1945 San Francisco Conference, which founded the United Nations and drafted the United Nations Charter.