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He worked as a professor in the Department of Mathematics until 2000 when he was appointed professor of mechanics of materials at the Department of Materials Science in the University of Ioannina.
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He is widely published and has held senior positions at the University of Ioannina and the University of Western Macedonia.
For his contributions to the history of medieval Epirus, the city of Arta made him an honorary citizen in 1990, and he was awarded an honorary doctorate by the University of Ioannina in 1997.
John P. A. Ioannidis (born 1965 in New York City) is a professor and chairman at the Department of Hygiene and Epidemiology, University of Ioannina School of Medicine as well as adjunct professor at Tufts University School of Medicine and Professor of Medicine and Director of the Stanford Prevention Research Center at Stanford University School of Medicine.