Pico das Agulhas Negras can be seen to the northwest of Resende when driving between São Paulo and Rio de Janeiro on the Via Dutra highway, but this is only possible at a few points on the road, because of a lower mountain range close to the road that stands in the line-of-sight at most close places.
Many Brazilian highways pass through or start in São Paulo, such as BR-116, Rodovia dos Bandeirantes, Rodovia Raposo Tavares, the Rodovia Anhangüera, Rodovia dos Imigrantes, Rodovia Castelo Branco, and Via Dutra.