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Isotretinoin (13-cis-retinoic-acid; brand name Roaccutane), which is often used to treat severe acne, is such a strong teratogen that just a single dose taken by a pregnant woman may result in serious birth defects.
Spangenberg gained national recognition for his firm by stepping forward to represent Canadian children injured by the birth-defect-causing morning sickness medication Thalidomide.
Eli Bowen was born in Richland County, Ohio to Robert and Sarah Bowen with his undeveloped feet attached to the hips due to a rare birth defect - the so-called seal limbs, which was caused by a genetic disorder phocomelia.