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On May 1, 2008, it was announced that the U.S. government, in its trial against Trevor Graham, would have Mitchell, as well as Antonio Pettigrew as witnesses, with Mitchell to testify that Graham injected him with human growth hormone.
According to the report, Bigbie admitted to purchasing and using a variety of performance-enhancing substances from Kirk Radomski from 2001 to 2005, including human growth hormone, Deca-Durabolin, Sustanon, testosterone, and anti-estrogen drugs.
On June 21, 2006, in an ESPN The Magazine article by Amy K. Nelson, Crawford, who is now out of baseball, admitted to using the steroids Deca-Durabolin and Winstrol, human growth hormone and amphetamines from 1999–2001.
After an investigation, it was revealed that many top baseball athletes were connected with THG; the list included stars such as Jason Giambi, who would also confess to using human growth hormone and testosterone, Gary Sheffield, who admitted using the cream and the clear, albeit unknowingly.
Pharmaceutical companies Genentech and Eli Lilly, makers of human growth hormone, have worked to medicalize short stature by convincing the public that short stature is a disease rather than a natural variation in human height.