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A native of Goodwins Mills, Maine, Coombs made his major league debut in relief on June 8, 1933 in a home game against the New York Yankees at Shibe Park.
Ayala made his major league debut as the Mets' starting left fielder at Shea Stadium on August 27, 1974.
He made his major league debut on June 6, 2009, pitching 2 IP, giving up 4 runs, 3 hits including a home run, walking 1, and striking out 1.
He made his major league debut with the Orioles in 2006, but spent most of that season with AAA Norfolk.
He was the second-youngest player in the American League when he made his major-league debut, being older than 16-year old Carl Scheib.
He made his major league debut on September 14, 1988 as the starting catcher wearing #7, and played his final game on April 27, 2003 as the starting catcher wearing #12.
He posted a 2–3 with a 2.39 ERA in 10 starts for the Sea Dogs before making his major league debut on May 31 starting for Boston in place of the injured David Wells.
On April 7, 2009, Moreno made his Major League debut for the San Diego Padres against the Los Angeles Dodgers, pitching in 1 inning and getting a strikeout.
Robinson made his major league debut at age 24 on August 10, 1960 in a 6-0 White Sox home loss to the New York Yankees, starting in right field and going 0-for-3 against Art Ditmar.
He made his major league debut at age 23 on September 7, 1966 as the Indians' starting pitcher against Jim Lonborg and the Boston Red Sox at Cleveland Municipal Stadium.
Byrd made his major league debut on June 20, 1977, when he started a game against the Cleveland Indians at Exhibition Stadium.
Drafted by the Minnesota Twins in the 10th round of the 1986 MLB amateur draft, Reboulet would make his major league debut with the Twins on May 12, 1992, and appear in his final game during the 2003 season.
Despite his late conversion, McNertney developed into a good defensive catcher and made his major league debut at 27 with the White Sox in 1964.
Rather than return to the Oaks in 1937, he arranged a deal with the Pittsburgh Pirates, with whom he made his major league debut on April 30, 1937.
He made his major league debut on April 18, 1945, in a road game against the Philadelphia Athletics at Shibe Park.
Macha made his major league debut on September 14, 1974, going 1-for-1 in a 17-2 Pirates loss to the Expos at Jarry Park.
Drafted by the Philadelphia Phillies in the 5th round of the 1976 MLB amateur draft, Matuszek would make his major league debut with the Philadelphia Phillies on September 3, 1981, and appear in his final game on April 30, 1987.
He toiled one further season, 1960, in the minors (with the Denver Bears of the American Association) before finally making his Major League debut with the Tigers at age 30 on April 19, 1961.
Arizona Diamondbacks' pitcher Brad Ziegler, who made his major-league debut in May 2008, is a graduate of Odessa High School.
A native of Dundas, Ontario, Wood made his major league debut on 15 July 1885 with the Buffalo Bisons, the team which also featured on its roster his brother, Fred Wood.
He was traded to the Chicago Cubs before the 1986 season, and made his major league debut with them in 1989.
He made his major league debut on August 2, and fouled out pinch hitting for pitcher Max Leon in his only at-bat.
He made his Major League debut for the Rockies on July 16, 2005 against the Cincinnati Reds and recorded his first hit in that game, a single to right field off of Todd Coffey.
Harkness made his major league debut on September 12, 1961 against the Phillies, working out a walk in five pitches against pitcher Chris Short as a pinch hitter in the ninth inning in a 19–10 loss at the Los Angeles Memorial Coliseum.
With the Indians already behind 11-1 to the Minnesota Twins, Agee made his major league debut on September 14 at Metropolitan Stadium pinch-hitting for pitcher Bill Dailey in the ninth inning.