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Joseph John Sisco (October 31, 1919 – November 23, 2004) was a diplomat who played a major role in then-Secretary of State Henry Kissinger's shuttle diplomacy in the Middle East and whose career in the State Department spanned five presidential administrations and numerous foreign-policy crises.
He served as an American ambassador to Saudi Arabia and Egypt, assisted Henry Kissinger's Mideast shuttle diplomacy effort, worked with Egyptian President Anwar el-Sadat throughout the Camp David Accords, and dodged a Libyan hit team.