It runs north-east from Gothersgade at Nørreport Station to Georg Brandes Plads, between the Copenhagen Botanical Gardens and Rosenborg Castle Gardens, and continues straight to a large junction at the southern end of Oslo Plads, near Østerport Station, where it turns into Folke Bernadotte Allé
The section from Kronprinsessegade to Øster Voldgade follows the walled north-eastern margin of Rosenborg Castle Garden and the next section, from Øster Voldgade to the intersection with Farimagsgade, named Sølvtorvet (English: "Silver Square") although it is little more than a busy street junction, separates Copenhagen Botanical Garden from Østre Anlæg.