The show first aired on Opening Day in 1997 with a game between the defending World Series champion New York Yankees and the Seattle Mariners.
Major League Baseball (MLB) has a more extreme way of scheduling since interleague games are done rarely, and were only introduced in 1997, plus the fact that interleague games do not exactly have concrete rules, save for the number of rest days and doubleheaders.
Major League Baseball | National Football League | baseball | National Hockey League | 1997 | UEFA Champions League | Premier League | Major | Australian Football League | rugby league | Major League Soccer | National League | League of Nations | 1997 in music | UEFA Europa League | American League | Canadian Football League | the season | Arena Football League | the Football League | American Hockey League | Texas Rangers (baseball) | Bulgarian Hockey League | Football League First Division | Football League Second Division | minor league baseball | Champions League | National Baseball Hall of Fame and Museum | Super League | John Major |