X-Nico

unusual facts about 2- and 4-Quinolones


Conrad–Limpach synthesis

With much of the literature on the synthesis of quinolines, there is some discrepancy on whether a substituted 4-hydroxyquinoline or a substituted 4-quinolone is the final product of the Conrad-Limpach synthesis.


Levofloxacin

Like all quinolones, it functions by inhibiting the two type II topoisomerase enzymes, namely DNA gyrase and topoisomerase IV.


see also