The settlement was serving now as a rest area for merchants traveling to and from the nearby fluvial port town of Gamarra and Ocaña (present-day Department of North Santander).
La Gloria is situated to the Eastern margin of the Magdalena River, it borders the north with the municipalities of Tamalameque and Pelaya, the south with the municipalities of Gamarra and Aguachica, the West with the Bolívar Department and the east with the Norte de Santander Department.